

It is often viewed as having a lower risk of dependence than typical opioids but may still be habit- forming. government as a narcotic, but is a synthetic medication. Phantom limb pain is pain that persists after a limb has been amputated. Opioids such as oxycodone (Oxecta, Ox圜ontin), morphine (brand names MS Contin, Kadian, and others), and Tramadol (Ultra, Conzip, and others) treat diabetic peripheral neuropathy, post-herpetic neuropathy, polyneuropathy, and phantom limb pain. See Opioids for Back Pain: Potential for Abuse, Assessment Tools, and Addiction Treatment

High doses of opioids typically are needed to provide significant pain relief for neuropathic conditions.

Opioids can be helpful in certain cases, but are often discouraged because of concerns about overdoses, abuse, dependence, and the effects of long-term use. Less common side effects include, but are not limited to, a cough, tightness in the chest/wheezing, and breathing problems. Lidocaine (brand names Lidoderm, Xylocaine, and others) and capsaicin (brand names Zostrix, Trixaicin, and others) are common topical treatments.įlushing of the face as well as swelling, burning, and other irritation in the area where the medication is applied are the most common side effects. Multiple applications are typically needed for significant pain relief. Little of the medication reaches the bloodstream, so cognitive side effects are avoided. Topical treatments may be a good option for individuals who cannot tolerate or prefer not to take oral medication. The medication in these products is absorbed into the skin, either numbing the area or relieving pain. Usually available as a patch, gel, or cream, topical treatments can be helpful for localized neuropathic pain. Women should ask their doctor before taking antidepressants or any other medication during pregnancy. Antidepressants also may increase the risk of suicidal thoughts.

Side effects and risks with antidepressants may include, but are not limited to, heart problems, constipation, drowsiness, light-headedness, weight gain, dry mouth, and nausea. Options include escitalopram (brand name Lexapro), paroxetine (brand names Brisdelle, Paxil, and others), and fluoxetine (brand names Prozac, Sarafem, and others). This group of medications is not typically the first choice by itself, but may be helpful in combination with tricyclic antidepressants or if other medications are not well tolerated.
